Integrated 7T MRI and SPECT Systems for Small-Animal Imaging
نویسندگان
چکیده
Purpose MRI and single-photon emission computed tomography (SPECT) provide complimentary information which could aid in the diagnosis of various diseases. However, acquiring images from both modalities can been problematic. Until recently, SPECT systems could not be integrated with MRI systems due to the use of photomultiplier tubes which do not function in high magnetic fields. The development of semiconductor-based nuclear radiation detectors now allow for the operation of SPECT components within high magnetic fields. We have successfully operated such a SPECT system placed within the bore of a whole-body 4 T MRI system [1]. For a small-bore MRI system, a SPECT system could be placed immediately adjacent and co-axial to the magnet for efficient sequential imaging. Previously constructed ‘back-to-back’ systems were limited to MRI field strengths of only 0.1 T [2,3]. In this study, we present an integration of 7 T MRI and SPECT systems for small-animal imaging.
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